Sleeping tablets are among the most widely prescribed medicines, and disturbances in sleep are associated with a wide range of medical and psychiatric conditions. An understanding of these mechanisms is of paramount importance to our society. Although the function or functions of sleep are still unresolved, great progress has been made in understanding the brain mechanisms that control sleep and wakefulness. The purpose of sleep is one of the great unsolved mysteries of biology and has fascinated people for millennia. Sleep disruption interferes with the normal restorative functions of NREM and REM sleep, resulting in disruptions of breathing and cardiovascular function, changes in emotional reactivity, and cognitive impairments in attention, memory, and decision making.
Genetic studies suggest that brain mechanisms controlling waking and NREM sleep are strongly conserved throughout evolution, underscoring their enormous importance for brain function. Strong activation of limbic regions during REM sleep suggests a role in regulation of emotion.
Rapid-eye-movement (REM) sleep results from the interaction of brain stem cholinergic, aminergic, and GABAergic neurons which control the activity of glutamatergic reticular formation neurons leading to REM sleep phenomena such as muscle atonia, REMs, dreaming, and cortical activation. Non-rapid-eye-movement (NREM) sleep results in conservation of brain energy and facilitates memory consolidation through the modulation of synaptic weights. Local, activity-dependent factors modulate the amplitude and frequency of cortical slow oscillations. Sleep results from the inhibition of wake-promoting systems by homeostatic sleep factors such as adenosine and nitric oxide and GABAergic neurons in the preoptic area of the hypothalamus, resulting in large-amplitude, slow EEG oscillations. Multiple interacting neurotransmitter systems in the brain stem, hypothalamus, and basal forebrain converge onto common effector systems in the thalamus and cortex. Wakefulness promoting systems cause low-voltage, fast activity in the electroencephalogram (EEG). (551-479 B.C.This review summarizes the brain mechanisms controlling sleep and wakefulness. Peace, Oneness, Illumination, Enlightenment, Experience as the witness Non-physiological response to the field of consciousness itself 'Out of many, one', Great Seal of the United States constitutionįictional place, as concept in the film Lost Horizon Greek philosopher, as a realized spiritual beingĬhristian festivity, idea of Peace for Humanityīy James Madison, from the U.S. (788-820) indian hindu teacher of advaita Holy scripture, book, without revelation, King James translation Indian Prince, buddhist zen monch from China
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The void, state of nothingness, reality as awareness, full enlightenment, attributes of: omnipresence, omniscience, omnipotence Translation of the bible by George Lamsa from the aramaic Mystic scripture based on the book KabbalaĬarried through the world by the Maitreya Project Yoga of selfless service from indian yogic philosophyįirst apostle of Jesus, under floor of the Basilica in RomeĮgyptian drafter of the five books of MoseĬonsciousness of the apostle of Jesus Christ, going from 905-990 (6 B.C.-36 A.D.) holy man, sermonizer, enunciator of Jesus (770-850 A.D.) chinese zen buddhist masterįifth book by David R. Hawkins, M.D., Ph.D.įourth book by David R. The circumstances of birth and life are karmically perfectĪlso Jhana, buddhist phrasing for meditation from vedas philosophy Life cannot be destroyed, it can only change formĬreation and Evolution are one and the same realityĬonsciousness is the irreducible stratum of all that exists
The Absolute, Brahman, Christ consciousness, level of avatars God, the Father, the Creator, the Almighty The whole universe awaits discovery on a new level of understanding, out of which arise compassion and wisdom." The normal response to this is disbelief, followed by paradigm shock, but then, curiosity pervails. "The first doubt block to be overcome is the startling discovery that the truth about anything whatsoever is readily available in a few seconds just for the asking.
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